Tattoo aftercare starts as soon as your tattoo is done. Buy Bactrim Pills Online - Sulfamethoxazole Nunc pellentesque Bactrim (co-trimoxazole) is typically recommended for patients diagnosed with microbial infections. Septra and Bactrim (sulfamethoxazole-trimethoprim) are some common brand names you might encounter. American Society for Microbiology, Washington, D.C. 1980; Vol. In severe cases of infection, antibiotic treatments may last for weeks or months. Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Your doctor may adjust this dose if needed. HHS Vulnerability Disclosure, Help Likewise, fava beans have a similar reaction and are best to avoid as well. Getting a tattoo or piercing is a big decision. The minimum amount of benzyl alcohol at which serious adverse reactions may occur is not known [see WARNINGS AND PRECAUTIONS]. Anti-Rejection Drugs:If you have had an organ transplant and/or are on anti-rejection medication, getting a tattoo might not be in your best interest. Complete the full course as prescribed (unless instructed not to do so by your doctor) to reduce the risk of resistant bacteria developing. BACTRIM, given at a common clinical dosage, increased the phenytoin half-life by 39% and decreased the phenytoin metabolic clearance rate by 27%. Sulfonamides, including sulfonamide-containing products such as BACTRIM, should be discontinued at the first appearance of skin rash or any sign of adverse reaction. When administered together as BACTRIM, neither trimethoprim nor sulfamethoxazole affects the urinary excretion pattern of the other. Fatalities associated with the administration of sulfonamides, have occurred due to severe reactions, including, Stevens-Johnson Syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia and other blood dyscrasias. Sulfamethoxazole was not carcinogenic when assessed in a 26-week tumorigenic mouse (Tg-rasH2) study at doses up to 400 mg/kg/day sulfamethoxazole; equivalent to 2-fold the human systemic exposure (at a daily dose of 800 mg sulfamethoxazole b.i.d. This can cause the area to heal improperly, which may make you more susceptible to infections. Luckily, this isn't always the case. Instruct patients to maintain an adequate fluid intake in order to prevent crystalluria and stone formation. These effects are reversible by folinic acid therapy. You may need blood and urine tests, and this medicine may be stopped based on the results. Weighing 30 kg3 teaspoonfuls (15 mL) of oral liquid or 1 tablet 2 times a day for 10 days. Yet several antibiotics can cause red blood cells to break down. No other systems have been tested and therefore no others can be recommended. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Bactrim only for the indication prescribed. U.S. National Library ofMedicine. information highlighted below and resubmit the form. This content does not have an Arabic version. However, keep in mind that it may be difficult to know what exactly is in tattoo inks as they arent regulated in any way. Dr. Hiep Le answered Nephrology and Dialysis 44 years experience In in vitro Comet, micronucleus and chromosomal damage assays using cultured human lymphocytes, trimethoprim was positive. Sulfamethoxazole and trimethoprim are are both antibiotics that treat different types of infection caused by bacteria. Propylene glycol toxicity can lead to acute kidney injury, CNS toxicity, and multi-organ failure. Close monitoring of serum potassium is warranted in these patients. Avoid coadministration of BACTRIM with drugs that are substrates of CYP2C8 and 2C9 or OCT2. Can I Work Out With a New Piercing or Tattoo? Blood dyscrasias and jaundice are potential late manifestations of overdosage. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Complete blood counts should be done frequently in patients receiving sulfonamides. Fava beans (also known as broad beans) can trigger a hemolytic attack if you have G6PD deficiency. and transmitted securely. All rights reserved. Did you know that favism is another term for G6PD deficiency, especially in severe cases? severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose); swelling, bruising, or irritation around the IV needle; increased thirst, dry mouth, fruity breath odor; new or worsening cough, fever, trouble breathing; high blood potassium - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; low blood sodium - headache, confusion, problems with thinking or memory, weakness, feeling unsteady; or. Tell your doctor if you experience serious side effects of Bactrim including: BACTRIM (trimethoprim and sulfamethoxazole) injection, a sterile solution for intravenous infusion only, is a combination of sulfamethoxazole, a sulfonamide antimicrobial, and trimethoprim, a dihydrofolate reductase inhibitor antibacterial. For prevention of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP): Adults800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim once a day. Is Aquaphor Recommended After Getting a Tattoo? Mycobacterium fortuitum-induced persistent parotitis: successful therapy with clarithromycin and ciprofloxacin. health information, we will treat all of that information as protected health He had been treated unsuccessfully with cephalexin. Repeat these steps about 4 times a day for at least 4 days. The mean renal clearance of trimethoprim was significantly lower in geriatric subjects compared with young adult subjects (19 mL/h/kg vs. 55 mL/h/kg). Yes, Bactrim is commonly used to treat UTIs. Nov 1973;128 (Suppl): S657-S663. If a patient develops skin rash or any sign of an adverse reaction, reevaluate therapy with BACTRIM [see WARNINGS AND PRECAUTIONS]. Some epidemiologic studies suggest that exposure to BACTRIM during pregnancy may be associated with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular abnormalities, urinary tract defects, oral clefts, and club foot (see Human Data). doctor said i should try for 7 days if i can but 6 if it looks healed could work. In in vitro and in vivo tests in animal species, sulfamethoxazole/trimethoprim did not damage chromosomes. 2015 Jun 16;21(6):13030/qt8mr3r4f0. An allergic reaction can also lead to anaphylactic shock. You should refer to the prescribing information for Bactrim for a complete list of interactions. A hemolytic crisis is when your body destroys red blood cells faster than it can make new ones. Hence, there is potential for an additive myelotoxicity when coadministered. . Avoid use of BACTRIM in patients with impaired renal or hepatic function, in those with possible folate deficiency (e.g., the elderly, chronic alcoholics, patients receiving anticonvulsant therapy, patients with malabsorption syndrome, and patients in malnutrition states) and in those with severe allergies or bronchial asthma. If the medical condition is only a risk to you and not to the artistsuch as a heart conditionyou're just hurting yourself by not disclosing it. Chen CC, Chen SY, Chen YS, Lo CY, Cheng PW. The average household teaspoon may not hold the right amount of liquid. He denied similar symptoms with previous tattoos. Safrin S, Lee BL, Sande MA. Also, although an artist has the right to refuse service to a potential client based on health reasons, you also have the right to take your business elsewhere if you feel the artist was in error or being unfair. Sulfamethoxazole stops bacteria from making dihydrofolic acid and trimethoprim prevents the formation of tetrahydrofolic acid; both are significant steps in the formation of nucleic acids and proteins essential to many bacteria. May be taken with or without food. (2012). Areola micropigmentation: Information for patients. 8. Tattoos and infection: Think before you ink. We comply with the HONcode standard for trustworthy health information. Discontinue and seek urgent medical advice if a skin rash develops. red skin lesions, often with a purple center. The sulfamethoxazole component belongs to the class of medicines known as sulfonamides, and the trimethoprim component belongs to the class of medicines known as folic acid inhibitors. A tattoo blowout looks like your tattoo is bleeding or blurry outside the lines. Clostridioides difficile-associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including BACTRIM, and may range in severity from mild diarrhea to fatal colitis. It is in no way related to Penicillin. With basic care and good hygiene, most new tattoos heal within a few weeks, but some people may develop an infection that requires medical attention. Eveleth R. (2012). If the artist decides that they cannot, in good conscience, proceed with the tattoo or piercing, it's because they don't want you to get hurt. Patients with severely impaired renal function exhibit an increase in the half-lives of both components, requiring dosage regimen adjustment [see DOSAGE AND ADMINISTRATION]. Trimethoprim-sulfamethoxazole, otherwise known as Bactrim or Septra, is a commonly prescribed antibiotic for soft tissue infections. Patients who are slow acetylators may be more prone to idiosyncratic reactions to sulfonamides. If upon visual inspection there is cloudiness or evidence of crystallization after mixing, the solution should be discarded and a fresh solution prepared. It is an almost white, odorless, tasteless compound with a molecular weight of 253.28 and the following structural formula: BACTRIM is indicated in the treatment of Pneumocystis jirovecii pneumonia in adults and pediatric patients two months of age and older. When renal function is impaired, a reduced dosage should be employed, as shown in Table 2. Would you like email updates of new search results? If your tissue has died due to the infection (necrosis), surgery may be needed to remove it. Cookie Notice The following information includes only the average doses of this medicine. Preterm, low-birth weight infants may be more likely to develop these reactions because they may be less able to metabolize benzyl alcohol. Additional monitoring of blood glucose may be warranted. My doc doesn't know if it would affect it or not. Drug information provided by: Merative, Micromedex. Advise pregnant women of the potential harm of BACTRIM to the fetus (see Clinical Considerations). Thrombophlebitis has been observed. As with any skin infection, in severe cases bacteria can enter your bloodstream and actually become life-threatening." Keep in mind, tattoo infections are usually deeper in the skin as the needle. The patient was treated with a 2-month course of oral trimethoprim-sulfamethoxazole (160mg/800mg twice daily) and ciprofloxacin (250 mg twice daily), with clinical improvement at follow up after three weeks of the antibiotic regimen. 11. ! Arch Pathol Lab Med. The percent of dose excreted in urine over a 12-hour period following the intravenous administration of the first dose of 240 mg of trimethoprim and 1200 mg of sulfamethoxazole on day 1 ranged from 17% to 42.4% as free trimethoprim; 7% to 12.7% as free sulfamethoxazole; and 36.7% to 56% as total (free plus the N4-acetylated metabolite) sulfamethoxazole. Marinella MA. Symptom relief is often seen within 3 days of starting treatment. Head Neck. But getting a tattoo does carry some risk: Inserting an ink-covered needle into your skin has the potential to introduce foreign matter or infections into your body. But its not clear if completely avoiding all legumes is actually necessary. Trimethoprim is metabolized in vitro to 11 different metabolites, of which, five are glutathione adducts and six are oxidative metabolites, including the major metabolites, 1- and 3-oxides and the An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. While we understand if you're not 100% comfortable disclosing medical information to your tattoo artist, you should know why it matters in the first place. We report an uncommon case of a cutaneous infection with Mycobacterium fortuitum arising in a new tattoo. Avoid use of BACTRIM in patients with porphyria or thyroid dysfunction. People with G6PD deficiency can tolerate most antibiotics. Bactrim is available as a generic under the name sulfamethoxazole/trimethoprim. 2007 Nov;29(11):1061-4. doi: 10.1002/hed.20626. Aquaphor is a product that tattoo artists often recommend to be used on new tattoos during aftercare. This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. Uses. Levels of BACTRIM in breast milk are approximately 2 to 5% of the recommended daily dose for pediatric patients over two months of age. (2012). If this is the case, your symptoms should fade after a few days. To provide you with the most relevant and helpful information, and understand which Last reviewed on RxList: 11/25/2020
Bactrim may also be prescribed to children over 2 months old, and the dosage is based on the childs weight. The most common adverse reactions are gastrointestinal disturbances (nausea, vomiting, and anorexia) and allergic skin reactions (such as rash and urticaria). Reactions have included Stevens-Johnson syndrome (a disorder involving the skin and mucous membranes), liver disease, and blood disorders such as thrombocytopenia (low platelets). How Can You Increase Your Red Blood Cells? Make sure that all items that touch your skin have been properly sterilized. Rapidly growing mycobacteria have emerged as a cause of tattoo-associated cutaneous infection in recent years. red, irritated eyes. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use bactrim only for the indication prescribed. sores in the infected area, filled with pus or fluid. Do not use Bactrim if you are pregnant. Keep from freezing. 12. Antibiotics: Disclose all antibiotics to your tattoo artist, and . extreme thirst. other information we have about you. Cases of interactions with other OCT2 substrates, memantine and metformin, have also been reported. BACTRIM is contraindicated in pediatric patients younger than two months of age because of the potential risk of bilirubin displacement and kernicterus [see CONTRAINDICATIONS]. doi:10.1002/14651858.CD009435.pub2. It is very important to carefully follow the instructions for taking the antibiotic; this means . Weighing 64 kg8 teaspoonfuls (40 mL) or 4 tablets (or 2 DS tablets) 4 times a day for 14 to 21 days. Some people recommend removing all legumes (such as beans, peas, lentils, or peanuts) from your diet. This practice includes employing preventative measures like wearing gloves and other protective gear and extends to avoiding contact with the client's body fluids. the unsubscribe link in the e-mail. Alternatively, other epidemiologic studies did not detect statistically significant associations between BACTRIM exposure and specific malformations. Evaluation for hyponatremia and appropriate correction is necessary in symptomatic patients to prevent life-threatening complications. For oral dosage forms (liquid or tablets): Adults1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 10 to 14 days. 1. The https:// ensures that you are connecting to the You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. If you have a medical condition or are on any kind of prescription medication, it is crucial that you disclose itto your artist before any tattoo or piercing procedure. Severe skin reactions, generalized bone marrow suppression [see WARNINGS AND PRECAUTIONS, ADVERSE REACTIONS], a specific decrease in platelets (with or without purpura), and hyperkalemia are the most frequently reported severe adverse reactions in elderly patients. Unable to load your collection due to an error, Unable to load your delegates due to an error. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory . Mayo Clinic does not endorse companies or products. 2023 Dotdash Media, Inc. All rights reserved. Each 5 mL contains 80 mg trimethoprim (16 mg/mL) and 400 mg sulfamethoxazole (80 mg/mL) compounded with 40% propylene glycol, 10% ethyl alcohol and 0.3% diethanolamine; 1% benzyl alcohol and 0.1% sodium metabisulfite added as preservatives, water for injection, and pH adjusted to approximately 10 with sodium hydroxide. 10. Keep well hydrated with fluids to avoid the development of crystals in the urine or kidney stones. To do so may increase the chance of side effects. You may need more frequent check-ups or medical tests if you also use medicine to treat depression, diabetes, seizures, or HIV. pain, tenderness, or swelling of the foot or leg. Last updated on Oct 18, 2021. Aspirin is often used to treat pain or inflammation. (2016). Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Last updated on March 1, 2023. Revised: Jul 2020. To help reduce the development of drug-resistant bacteria and maintain the effectiveness of Bactrim, this medicine should be used only to treat infections that are proven, or strongly suspected, to be caused by susceptible bacteria. Take Bactrim exactly as prescribed by your doctor. Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis carinii pneumonia. Increased digoxin blood levels can occur with concomitant BACTRIM therapy, especially in elderly patients. . Talk to your doctor if you have G6PD deficiency and need to take antibiotics. Treatment failure and excess mortality were observed when BACTRIM was used concomitantly with leucovorin for the treatment of HIV positive patients with Pneumocystis jirovecii pneumonia in a randomized placebo controlled trial.4 Avoid coadministration of BACTRIM and leucovorin during treatment of Pneumocystis jirovecii pneumonia. In elderly patients concurrently receiving certain diuretics, primarily thiazides, an increased incidence of thrombocytopenia with purpura has been reported. While there are no large, prospective, well-controlled studies in pregnant women and their babies, some retrospective epidemiologic studies suggest an association between first trimester exposure to BACTRIM with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular abnormalities, urinary tract defects, oral clefts, and club foot. Severe and symptomatic hyponatremia can occur in patients receiving BACTRIM, particularly for the treatment of P. jirovecii pneumonia. Clinical signs, such as rash, sore throat, fever, arthralgia, cough, shortness of breath, pallor, purpura or jaundice may be early indications of serious reactions. 7 Things You Should Avoid If You Have G6PD Deficiency. Some epidemiologic studies suggest that exposure to BACTRIM during pregnancy may be associated with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular malformations, urinary tract defects, oral clefts, and club foot. Studies in pregnant rabbits showed increased fetal loss at approximately 6 times the human dose on a body surface area basis (see Animal Data). Like other sulfonamide-containing drugs, BACTRIM potentiates the effect of oral hypoglycemic that are metabolized by CYP2C8 (e.g., pioglitazone, repaglinide, and rosiglitazone) or CYP2C9 (e.g., glipizide and glyburide) or eliminated renally via OCT2 (e.g., metformin). However, if you have G6PD deficiency, your body makes a smaller amount of G6PD, which can lead to anemia. This monograph has been modified to include the generic and brand name in many instances. Brumfitt W, Pursell R. Trimethoprim/Sulfamethoxazole in the Treatment of Bacteriuria in Women. What Clinicians Should Know About the QT Interval. (twice a day). Disclaimer. In vitro studies have shown that bacterial resistance develops more slowly with both sulfamethoxazole and trimethoprim in combination than with either sulfamethoxazole or trimethoprim alone. Oct 1994;170(4):912-7. Active against a wide range of susceptible strains of gram-positive and gram-negative bacteria, such as. We recommend trimethoprim-sulfamethoxazole (TMP-SMX) as the treatment of choice for PCP of any severity in patients without HIV . During treatment, ensure adequate fluid intake and urinary output to prevent crystalluria. MedlinePlus. Universal Precautions is a set of precautionary steps defined by the Center for Disease Control (CDC) used to prevent the spread of disease. Federal government websites often end in .gov or .mil. low blood cell counts - fever, chills, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath. DOI: Mekaru S. (2011). One in five U.S. adults now has a tattoo. It has been reported that BACTRIM may prolong the prothrombin time in patients who are receiving the anticoagulant warfarin (a CYP2C9 substrate). Removal may require special treatment in the clinic or hospital. Monitor therapeutic response and adjust dose of TCA accordingly. When administering these drugs concurrently, one should be alert for possible excessive phenytoin effect. The formulation of N 4-hydroxy metabolite is mediated via CYP2C9. Probably not. The syndrome is a complication of blood cancers like leukemia. RxList does not provide medical advice, diagnosis or treatment. Ramakrishnan K, et al. Bactrim and Bactrim DS contain the same active ingredients at different strengths. Bactrim could make you sunburn more easily. Sulfite sensitivity is seen more frequently in asthmatic than in non-asthmatic people. Tattoos are an increasingly common sight. This interaction should be kept in mind when BACTRIM is given to patients already on anticoagulant therapy, and the coagulation time should be reassessed. BACTRIM may cause fetal harm if administered to a pregnant woman. See your doctor if you experience one or more of the following: A staph infection is one type of infection you might get with a tattoo. Causes and Treatment of Drug-Induced Hemolytic Anemia, Uses, Side Effects, and Procedure of a Bilirubin Test, When Iron Deficiency Anemia Is Not What It Appears to Be, How to Keep Yourself Safe Without a Spleen, The Difference Between Sulfa and Sulfite Allergies, Sulfite Allergy Overview and What to Avoid, Glucose-6-phosphate dehydrogenase deficiency, Rasburicase-induced hemolytic anemia in an adolescent with unknown glucose-6-phosphate dehydrogenase deficiency, Aspirin safety in glucose-6-phosphate dehydrogenase deficiency patients with acute coronary syndrome undergoing percutaneous coronary intervention, Henna causes life threatening haemolysis in glucose-6-phosphate dehydrogenase deficiency, Sulfa drugs, including Septra and Bactrim. 1 Sulfamethoxazole and trimethoprim combination is an antibiotic. In vitro studies suggest that trimethoprim is a substrate of P-glycoprotein, OCT1 and OCT2, and that sulfamethoxazole is not a substrate of P-glycoprotein. All of these 11 patients had normal renal function, and their ages ranged from 17 to 78 years (median, 60 years).11, Pharmacokinetic studies in children and adults suggest an age-dependent half-life of trimethoprim, as indicated in Table 5.12, Table 5: Half-life of Trimethoprim (TMP) in Pediatric Patients and Adults. They can tell you what's safe to take. Fortunately, most people with G6PD deficiency dont have problems most of the time. If an infection isnt treated soon enough or cant be treated properly because the bacteria have become resistant to an antibiotic, abscesses can result. Skin and soft tissue infections. The risk of side effects may be higher in the elderly. include protected health information. Avoid administration by rapid infusion or bolus injection. If signs of bone marrow depression occur, the patient should be given leucovorin 5 to 15 mg daily until normal hematopoiesis is restored. BACTRIM is indicated in the treatment of enteritis caused by susceptible strains of Shigella flexneri and Shigella sonnei in adults and pediatric patients two months of age and older. There are other medications that only cause red cell breakdown if taken in high doses. Pharmacokinetic values for sulfamethoxazole in geriatric subjects were similar to those observed in young adult subjects. All rights reserved. The presence of 10 mg percent sulfamethoxazole in plasma decreases the protein binding of trimethoprim by an insignificant degree; trimethoprim does not influence the protein binding of sulfamethoxazole. In rats, oral doses of either 533 mg/kg sulfamethoxazole or 200 mg/kg trimethoprim produced teratologic effects manifested mainly as cleft palates. 1996-2023 RxList, Inc. An Internet Brands company. Talk to your doctor or pharmacist before taking any other medications including those bought over the counter, because some may not be compatible with Bactrim. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Common medications that may interact with Bactrim include: Note that this list is not all-inclusive and includes only common medications that may interact with Bactrim. Ask yourself this: Is a tattoo or piercing really worth dying for? All rights reserved. The increased procainamide and NAPA plasma concentrations that resulted from the pharmacokinetic interaction with trimethoprim are associated with further prolongation of the QTc interval. Bactrim should not be given to a child younger than 2 months old. May interact with several other drugs including thiazides, warfarin, phenytoin, leucovorin, methotrexate, digoxin, and medications for diabetes. Cases of hypoglycemia in non-diabetic patients treated with BACTRIM have been seen, usually occurring after a few days of therapy. BACTRIM-induced thrombocytopenia may be an immune-mediated disorder. Aquaphor is a skin care staple for many people who have dry, chapped skin or lips. According to the WebMD, staph infection has been reported among unlicensed tattoo artists in at least three states. What Type of Cancer Causes Low Hemoglobin (Anemia)? They recommend testing people for G6PD deficiency before they take primaquine. Pneumocystis jirovecii Pneumonia (1.1) Shigellosis (1.2) Remove the bandage 3 to 5 hours after youve gotten the tattoo. Discontinue BACTRIM if propylene glycol toxicity is suspected [see ADVERSE REACTIONS]. Table 2: Impaired Renal Function Dosage Guidelines. Tattoo infections are usually easy to treat and even easier to prevent. BACTRIM (sulfamethoxazole and trimethoprim) injection is supplied as follows: 10-mL Vials, containing 160 mg trimethoprim (16 mg/mL) and 800 mg sulfamethoxazole (80 mg/mL) for infusion with 5% dextrose in water. Table 1: Dosage in Adults and Pediatric Patients (Two Months of Age and Older) by Indication. MisterBearcat 8 yr. ago Do not use two doses at one time. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. Patients allergic to sulfa compounds should not take Bactrim. 2001;14(5):410-414. Monitor patients for hematologic toxicity. After initial entry into the vial, the remaining contents must be used within 48 hours. Cochrane Database Syst Rev. In general, you should do the following to make sure the area heals properly: Once the tattooed area starts to form into scabs, use a moisturizer or lotion to keep your skin from getting too dry or damaged. Trimethoprim increases the plasma concentrations of procainamide and its active N-acetyl metabolite (NAPA) when trimethoprim and procainamide are coadministered.
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