This drug may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. These articles might help: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Mild side effects that have been reported with Topamax include: These side effects may be temporary, lasting a few days or weeks. Besides talking with your doctor, you can do some research on your own. By using our website, you consent to our use of cookies. Oxford University Press is a department of the University of Oxford. Can You Tell if You or Someone Else is About to Have a Seizure? This type of diet may raise the level of acid in your blood. (An active ingredient is what makes a drug work.) The following day, the patient was seen by her primary care physician, who switched from levetiracetam to topiramate 25 mg by mouth twice daily, with titration to topiramate 100 mg by mouth twice daily for maintenance therapy after 3 weeks. Topamax can cause certain side effects, some of which are more common than others. Learn more about some of the side effects Topamax may cause. I lost a bunch of weight on Topamax, for several reasons. You can learn more about how we ensure our content is accurate and current by reading our. You should not drink alcohol while youre taking Topamax. bleeding. Topiramate is a second-generation antiepileptic drug that is used in the treatment of seizure disorders and migraine headaches.7 Its use has been associated with weight loss; nausea and other gastrointestinal adverse effects; paresthesia in the hands, feet, or face; and cognitive and behavioral changes, including memory impairment, confusion, and reduced concentration. Topamax may cause serious side effects. Theyre also more likely to be born small for their gestational age. Examples of mild side effects that have been reported with Topamax include: * To learn more about this side effect, see the Side effects explained section below. Anticholinergic medications are associated with dry mouth, which can be interpreted as a metallic taste. No matter the type of carbonated beverage, each one tasted flat to her since starting topiramate therapy. You may be at higher risk of bone complications from metabolic acidosis if you already have bone problems. Do the side effects of topamax (topiramate) go away while taking it? Medication-related changes in taste are important to identify because such changes can negatively affect medication adherence, chronic disease management, and overall quality of life. If taken while breastfeeding, Topamax may pass into breast milk. They may recommend ways to ease your symptoms and determine whether you should keep taking Topamax. Are Topamax and Trokendi XR the same thing? I've been on Topamax for two months and I still can't stand to smell food, or taste what I eat or drink. One was the bad taste in my mouth all the time. Started topamax (topiramate) about 4 days ago and everything i eat runs right through me. Call 911 or your local emergency services number if you feel safe to do so. (2022). Glaucoma. However, missing doses may cause you to have symptoms of the condition youre using Topamax to treat. When its time for you to stop taking Topamax, your doctor will lower your dosage slowly over time. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide, This PDF is available to Subscribers Only. I've had minimal side effects -- lots of drinks and foods tasted strange at first, some low-grade headaches for the first couple of months -- but they've mostly disappeared. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. Its important to note that the dosage of Topamax is higher for seizures than for migraine headache prevention. YorkshireLass1. Topamax information for Healthcare Professionals. If you have glaucoma, Topamax may not be safe for you to take. If this condition isnt treated, it can lead to osteoporosis. Youll get first-hand stories from people living with this condition as well as tips for managing symptoms. Generic Topamax (topiramate) is used in combination with phentermine in a weight loss medication called Qsymia. Still looking for answers? It's not common but it can happen and did to me. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. .it is the topamax. You may need blood tests to make sure the level of acid in your blood is safe. Ok so I drink a crap ton of Coca Cola and for some reason it taste like it has Vodka in it lol. Taste . Topamax can increase your risk of depression and suicidal thoughts or actions. Serious side effects that have been reported and their symptoms include: * For more information about this side effect, see Side effect specifics below. inflammation of the tissue lining the sinuses. For me it stopped controlling my headaches after about 9 months. "Local trauma" to the tastebuds aka burning your tongue on hot stuff can change your sense of taste. Although research is ongoing, CBD is currently approved to treat seizures caused by two rare forms of epilepsy and tuberous sclerosis complex. what were you taking it for if you don't mind me asking? If I had known, I would have done it as a preventative. lol, Scan this QR code to download the app now. So you may have migraine headaches or seizures more often, or they may be more severe. Talk with your doctor to learn if Topamax is right for you. Topiramate ( Qudexy XR, Topamax, Trokendi XR) Valproic acid If the drugs don't work, you might have surgery to remove the damaged sensory receptors (olfactory mucosa) in your nasal cavity. I'm on it for migraines. Most people with epilepsy have warning signs during the prodromal or aura stages of a seizure, allowing extra time to get help. Below are a few questions you may want to ask: If you have migraine, consider signing up for Healthlines online newsletter. I don't even drink pop anymore. Dunkel and Hofmann also suggested that carbonic anhydrase 4, specifically, mediates the fizzy sensation experienced on drinking carbonated beverages. For example, Topamax may cause eye side effects,* such as glaucoma. In fact, carbonic anhydrase 4 may function as the principle CO2 taste sensor for the human body. Najafizade et al24 demonstrated that zinc supplementation increased perception of all sweet, sour, bitter, and salty tastes among patients with head or neck cancer undergoing radiotherapy. You may have mild side effects from Topamax. You may have changes in your sense of taste as a result of taking Topamax. Topamax (topiramate) is a prescription drug thats used to treat epilepsy and help prevent migraine headaches. Your doctor can help determine whether treatment with Topamax is safe for you. If you take Topamax while pregnant, youre encouraged to sign up with the North American Antiepileptic Drug Pregnancy Registry. Theyll recommend whether you should stop taking the drug. In fact, metallic taste is a reported adverse effect of over 300 medications.5 Medications with sulfhydryl groups, such as acetylcholinesterase inhibitors and antithyroid agents (propylthiouracil and methimazole), can cause metallic tastes. Although topiramate has multiple mechanisms of action, its carbonic anhydrase inhibitory effects are similar to those of acetazolamide.17. These side effects may be temporary, lasting a few days or weeks. Prior to the administration of topiramate, the patient had never experienced a loss of carbonation sensation while drinking numerous varieties of carbonated beverages throughout her life. Liver problems. Topamax may cause mood changes, including suicidal thoughts and behaviors. Thank you for submitting a comment on this article. Is the ketogenic diet right for autoimmune conditions? Mouths are sensitive to the effects of carbon dioxide, the substance that initiates the chemical pathway eliciting a fizzy and tingling sensation upon consumption of carbonated beverages.19 Results from Dunkel and Hofmanns18 study suggested that CO2 acts on the sour taste system as well as somatosensory pathways; the fizzy and tingling perception of carbonated beverages is likely due to gustatory and somatosensory inputs leading to multimodal sensation. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Its possible to have hair loss while taking Topamax. * This side effect can affect your ability to drive or safely operate machinery. Treat epilepsy * in. By 4 pm I'm. Department of Pharmacy Practice, Western New England University College of Pharmacy and Health Sciences, Address correspondence to Dr. Charbonneau (. 18 At the time of writing, 12 months had passed since topiramate initiation and the patients sense of carbonation had not returned to normal. This condition causes sudden, severe eye pain and blurry vision. If youve had an allergic reaction to Topamax or any of its ingredients, you should not take Topamax. And your doctor can use this information to adjust your treatment plan if needed. To learn more, please visit our. ', Can someone tell me if I will ever enjoy Coca Cola ever again? If you develop serious side effects while taking Topamax, call your doctor right away. Patients on topiramate therapy may find carbonation perception enhanced by drinking through a straw, and pharmacists can mention this as a potential counseling point. Mood problems or suicidal thoughts. Topamax is used to prevent migraine headaches and treat epilepsy in certain people. Salty foods taste saltier to me. Learn more. A bitter or bad taste in the mouth can occur after eating pungent or sour foods, but it can also stem from hormonal changes, poor oral health, medication use, stress, and many other factors. Frequent diarrhea. Examples of behavior and mood shifts Topamax can cause include: If you have any unusual shifts in mood while taking Topamax, call your doctor right away. In clinical studies, some people had fewer headaches after 4 weeks of treatment. Aswini et al23 noted reduced dental plaque when carbonated beverages were sipped with a straw; the straw concentrated the beverage on the tongue and minimized full-mouth exposure. A throbbing headache can occur due to migraine, tension, or neuralgia. BUT, I've taken the damn vaccine and I still wear my mask and I'm antisocial and have social anxiety so I don't even go outside and if I do (to walk my service dog) I stay away from people AND I STILL WEAR MY DAMN MASK so I kept thinking 'how on earth could I have gotten covid if I'm never around people. Its possible. Please check for further notifications by email. Try to remove any weapons, medications, or other potentially harmful objects. These problems include chronic obstructive pulmonary disease (COPD). 7 Its use has been associated with weight loss; nausea and other gastrointestinal adverse effects; paresthesia in the hands, feet, or face; and cognitive and behavioral changes, including memory impairment, confusion, You may need additional blood tests to monitor your levels while youre taking Topamax. When my doctor prescribed Topamax to me I was also in bed crying, we were on Zoom together, so maybe she said something about my taste buds going funky and I don't remember lol. If youre pregnant or planning a pregnancy, talk with your doctor before starting Topamax. Get answers from Cardiologists and top U.S. doctors, Our doctors evaluate, diagnose, prescribe, order lab tests, and recommend follow-up care. It may sometimes cause side effects, especially if you misuse it. In studies, this side effect was more common in people who took the drug to treat epilepsy than to prevent migraine headaches. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Like other drugs, Topamax can cause side effects. Doing so can worsen certain side effects of Topamax, such as dizziness and sleepiness. They can suggest ways to ease your symptoms. Your doctor can help determine whether treatment with Topamax is safe for you. This list doesnt include all possible mild side effects of the drug. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other commonly abused medications. And do not stop using Topamax unless your doctor recommends it. A 39-year-old Caucasian woman with longstanding epilepsy was initiated on topiramate therapy after experiencing a generalized seizure (she reported not taking any antiepileptic medication for years). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Following a ketogenic (keto) diet. For a list of side effects that were more common for each of these uses, see the More common side effects section above. You could also download a reminder app on your phone. Hair loss from Topamax is generally reversible. Post discussions, articles, and questions about uses, side effects, experiences, and any advances that may happen with this drug. 2023 Healthline Media LLC. The topiramate level was not rechecked after the first determination 17 days after topiramate initiation. These were rare in clinical trials. This side effect was somewhat common in clinical trials. For a general overview of Topamax, including details about its uses, see this article. Angiotensin-converting enzyme inhibitors, especially captopril, are among the drugs most commonly associated with taste disturbances, with strongly metallic, bitter, or sweet tastes having been reported.6. Your comment will be reviewed and published at the journal's discretion. and our Before taking Topamax, tell your doctor if you have mood problems such as depression. So I've been on Topamax since around September and I've only lost like 3 lbs unfortunately lol. For potential or actual medical emergencies, immediately call 911 or your local emergency service. You can also talk with your doctor or pharmacist. I am currently almost off Topamax now. This may include an over-the-counter antihistamine that you take by mouth, such as Benadryl (diphenhydramine). In most cases, side effects from Topamax are temporary. Learn more about types of seizures, causes and symptoms, and how you can help someone having, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Topamax (topiramate) tablets, for oral use; Topamax (topiramate capsules) sprinkle capsules, for oral use. Your doctor may prescribe a temporary treatment to help you manage these side effects for a short period of time. Mild side effects can occur with Topamax use. Cognitive side effects of Topamax can include: Your risk for cognitive side effects from Topamax increases if you start with a high dose, or your dose is increased quickly. Apparently it does make soda taste weird!!!!!!!!!! 6. Taste buds are each made up of taste receptor cells that bind to small molecules related to flavor. They may also recommend that you visit an eye doctor. Swallow the food mixture right away without chewing. Like most drugs, Topamax can cause an allergic reaction in some people. Talk with your doctor about the best way to feed your child if youre taking Topamax. Having reduced BMD could indicate that you have weakened bones. The topamax makes me SOOOOOO sleepy I can hardly keep my eyes open. Treatment with Topamax can cause a variety of cognitive side effects. For permissions, please e-mail: journals.permissions@oup.com. However, I'm really losing weight. Does metabolism change or just taste for foods/amts? Talk with your childs doctor, or a pharmacist, if you have questions about Topamaxs side effects in children. The conditions and factors to consider include: Bone problems, such as osteoporosis. At that time (and also during the initiation and titration of topiramate), the patient was not taking any other medications, vitamins, or supplements. Available for Android and iOS devices. How long does it take for Topamax to start working? Before taking Topamax, tell your doctor if you have kidney problems. Ask your doctor what other medications are better options for you. All rights reserved. anorexia, weight loss, difficulty with memory, taste perversion, diarrhea, hypoesthesia, nausea, abdominal pain and upper respiratory tract . Dysgeusia is a taste disorder. Lowered BMD could mean your bones are weakened. People with the condition feel that all foods taste sour, sweet, bitter or metallic. Examples include valproic acid and phenytoin (Dilantin). +0 GR gr07 24 April 2013 I'm on it for migraines. Make sure to call your doctor right away if you have symptoms that are severe or bother you. i'm on it and cannot drink anything with bubbles. Topamax can cause certain stomach-related side effects. Biotin is very important. Can i go off topamax (topiramate) after 12 days? More common side effects in people taking Topamax for migraine include: More common side effects in people taking Topamax for epilepsy include: Read on to learn about other mild and severe side effects that can happen with Topamax. They can recommend ways to reach or maintain a weight thats healthy for you. Learn the causes, treatments, and remedies for this type of headache. A systematic review of placebo-controlled trials of topiramate: how useful is a multiple-indications review for evaluating the adverse events of an antiepileptic drug? Topamax is known to pass into breast milk. Taking Topamax can cause hair loss as a side effect. The patient looked to online forums for patients with epilepsy and migraine for information on the phenomenon and found numerous reports of similar experiences from others taking topiramate on the websites epilepsy.org and migraine.org.9,10 In one such forum, someone suggested using a straw to help mitigate the adverse effect, and our patient found the suggestion helpful. In rare cases, Topamax can cause metabolic acidosis (too much acid in your blood). Keep in mind that Topamax may cause mood changes,* including depression. Many are mild and tend to go away on their own after a few days or weeks. What are the serious side effects of Topamax? They may recommend a different drug for your condition. Topamax may also affect weight and height in children taking the drug. A 39-year-old Caucasian woman with epilepsy had a generalized seizure after 12 years without use of antiepileptic medication. Mad that none of the doctors picked up on it. See the Topamax prescribing information for details. Metformin has also been associated with metallic taste, which tends to resolve after a few months of metformin use. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. You can register by visiting the program website or calling 888-233-2334. If a child takes Topamax, their doctor will check their growth. Topamax is approved to treat certain types of seizures and help prevent migraine headaches. After initiation of topiramate therapy, the patient began to experience an immediate change in her carbonation perception when drinking carbonated beverages; all carbonated beverages, including seltzer and beer, tasted flat. The patient remained on topiramate for the subsequent 12 months without her carbonation perception returning to normal but noted that drinking carbonated beverages through straws slightly mitigated the adverse effect. The list below includes factors to consider. Keep reading to learn about the common, mild, and serious side effects of Topamax and ways to deal with them. Maheswaran T, Abikshyeet P, Sitra G, Gokulanathan S, Vaithiyanadane V, Jeelani S. Linde M, Mulleners WM, Chronicle EP, McCrory DC. Yes, the risk of side effects from Topamax can depend on the strength you take. Taste perversion or taste dysgeusia in association with topiramate use has been reported in numerous randomized controlled trials; however, most of the trial reports did not define the specific manifestation of dysgeusia as carbonation dysgeusia.
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